By Ashim Datta, Vineet Rakesh
Equipped round challenge fixing, this publication lightly introduces the reader to computational simulation of biomedical shipping methods, bridging primary idea with real-world functions. utilizing this publication the reader will achieve an entire beginning to the topic, beginning with challenge simplification, enforcing it in software program, via to reading the consequences, validation, and optimization. Ten case reports, concentrating on rising components corresponding to thermal remedy and drug supply, with effortless to stick to step by step directions, offer ready-to-use templates for extra functions. resolution procedure utilizing the generally used instrument COMSOL Multiphysics is defined intimately; valuable biomedical estate facts and correlations are integrated; and historical past idea info is given on the finish of the ebook for simple reference. a mix of brief and prolonged routines make this booklet an entire direction package deal for undergraduate and starting graduate scholars in biomedical and biochemical engineering curricula, in addition to a self-study consultant.
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Extra info for An Introduction to Modeling of Transport Processes: Applications to Biomedical Systems
Not all regions need to be included in the computational domain. 7 where we have two regions – fluid (blood) and solid (arterial tissue surrounding the blood). Depending on the physical process in which we are interested, it may be possible to stay completely in the fluid, with the solid as the boundary condition. 7 How a problem involving both solid and fluid may be simplified to consider only solid (1), or only fluid (2). An appropriate boundary condition at the solid–fluid interface is needed for such simplification.
The transient term can be ignored if we expect the process to reach a steady state for most of the time period of interest. Convection The convection term in the heat or mass transfer equation represents the transport of energy or species, respectively, due to bulk flow. This term should be retained when the computational domain is a fluid, where movement (flow) is expected. Whether heat transport due to flow is stronger than that due to conduction can be checked by calculating the Peclet number (Pe = Re × Pr).
3, including the case studies in this book where a particular boundary condition has been used in a complete problem. In practice the choice of boundary condition has to be done carefully. A constant flux boundary condition, for example, may not stay that way for a long time. Consider drug delivery via a patch. One can start by assuming a constant flux (mass per unit area per unit time) of drug enters the tissue out of the patch, but a constant flux cannot continue for long. As more drug comes out, the drug content of the reservoir decreases and the flux drops.