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Biomedical Engineering

Biomedical science, engineering and technology by Dhanjoo N Ghista

By Dhanjoo N Ghista

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Concept: In order to simulate the left ventricle deformation during isovolumic contraction, we have modeled it as a pressurized fluid-filled thick-walled cylindrical shell supported by the aorta along its upper edge. The LV cylindrical model consists of an incompressible hyperelastic material with an exponential form of the strain energy function ψ. Biomedical Engineering Professional Trail from Anatomy and Physiology to Medicine and Into Hospital Administration: Towards Higher-Order of Translational Medicine and Patient Care 13 The contraction of the myocardial fibers causes active twisting and compression of the left ventricle, thereby compressing the blood fluid contained in it.

Stiffer lung) make breathing difficult. After these patients are mechanically ventilated, there is a need for accurate predictive indicators of lung-status improvement, for ventilator discontinuation through stepwise reduction in mechanical support, as and when patients are increasingly able to support their own breathing, followed by trials of unassisted breathing preceding extubation, and ending with extubation. So, in this section, we have provided a biomedical engineering analysis of the lung ventilator volume response to mechanical ventilation of COPD patients, and developed an index to assess the lung status as well as the basis of weaning the patient from ventilator support.

9) are the unknowns. So now, we substitute the stress expressions σrr and σθθ into the boundary conditions equations (of equilibrium between the internal pressure and the wall stresses σrr and σθθ, and between the internal pressure and wall stress σzz), and determine the best values of the constitutive parameters (bi) and the hydrostatic pressure to satisfy these equations. We then go back, and determine the stress expressions. We utilize the stress expressions for σzz and σθz, to determine the generated values of torsion (ΔT) and axial compression (ΔF),due to the contraction of the helically wound myocardial fibres.

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